Blood Transfusion and Apheresis:
Impact on Ionized Magnesium and Ionized Calcium
Impact on Ionized Magnesium and Ionized Calcium
Blood transfusion and apheresis protocols can be life-saving for critically ill patients by removing toxins, medications, destructive antibodies, or clotting factors from peripheral blood. However, blood levels of ionized magnesium (iMg) may drop as much as 60% at the end of an apheresis procedure. In addition, citrate used as an anticoagulant will bind with calcium, inducing hypocalcemia in many cases. In the current presentation, Dr. Sanford will discuss concerns around apheresis and transfusion procedures including the symptoms observed when magnesium or calcium are depleted and the effects of supplementation. She will also review the factors in different patient populations that influence the type of replacement fluid chosen, the necessity to monitor both iMg and iCa in these patients, and the importance of supplementing according to their ionized levels.
Primary Speaker:
Dr. Kimberly Sanford, MD.
Professor of Pathology, Medical Director of Transfusion Medicine – VCU Health
The importance of measuring ionized magnesium
in critically ill patients
in critically ill patients
Hypomagnesemia (low levels of magnesium) is associated with several clinical conditions, ranging from cardiovascular disease to transplantation and sepsis. Traditionally, total magnesium (tMg) measured in the laboratory is used to identify patients with hypomagnesemia. However, various studies have shown the clinical significance of using iMg, the biologically active form of magnesium, to correctly identify patients with hypomagnesemia. Dr. Naveen Bangia will review the clinical literature around the utility of measuring iMg in various clinical settings.
Speaker:
Naveen Bangia, PhD
Director, Medical and Scientific Affairs Nova Biomedical
Learning Objectives:
- • Understand the different patient-specific indications for plasmapheresis
- • Describe the changes in divalent cations calcium and magnesium and learn how to monitor these changes through appropriate testing and symptom identification
- • Explain the additional adverse events that may occur during apheresis
Dates and Times:
Thursday, June 12, 1 pm Eastern Time
Thursday, June 26, 10 am Eastern Time
Thursday, June 26, 10 am Eastern Time
Time:
6PM ET / 7PM GMT-3
Duration:
1 Hour
This program offers 1 hour of P.A.C.E. continuing education credits. Nova Biomedical is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E.® Program. This program has been approved by the American Association of Critical-Care Nurses (AACN), for 1.00 CERPs, Synergy CERP Category A, File Number 00000. Approval refers to recognition of continuing education only and does not imply AACN approval or endorsement of the content of this educational activity or the products mentioned.