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Medium Measurement Techniques Applicable to Cell Culture for Cell Therapy

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Our laboratory has previously demonstrated that fluctuations in medium composition in multilayer cultures of epithelial tissues (epidermal and corneal epithelial tissues) with three-dimensional structures can be used to understand the state of the epithelial tissues. In addition, this experience is applied to suspension cultures of iPS cell aggregates for the mass production recently. In this presentation, I will introduce our techniques of medium analysis and their applications. 


Masahiro Kino-Oka, Ph.D.
Professor in Department of Biotechnology& Director in Research Base for Cell Manufacturability, Graduate School of Engineering, Osaka University

Managing COVID-19 Respiratory Distress Patients Using an Expanded Test Blood Gas Analyzer

COVID-19 patients with respiratory distress require a comprehensive point-of-care test menu to manage their care. This seminar will examine the essential role of an expanded blood gas/critical care test menu, which includes BUN, creatinine, and ionized magnesium for managing acute respiratory distress COVID-19 and its co-morbidities: sepsis, stress hyperglycemia, acute kidney injury and arrhythmia.

 

Presenter: Bogdan Milojkovic, MD, Ph.D.

Global Director, Medical and Scientific Affairs Nova Biomedical

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This webinar is approved for 1.0 contact hour of CRCE credit by the American Association of Respiratory Therapists. Approval expires 10/7/2025.

Lactate as a Marker for Fetal Hypoxia

Available On Demand 

Prolonged intrapartum hypoxia can result in hypoxic ischemic encephalopathy (HIE), which affects1.5-2.5 of 1,000 newborns annually. Infants with HIE may develop permanent health conditions and disorders such as cerebral palsy, epilepsy, hearing and vision impairments, and more. During labor, fetal monitoring using cardiotocography (CTG) can screen for hypoxia. CTG has high sensitivity but low predictive value, thus secondary tools are needed to aid decisions regarding intervention.

Lactate accumulates in tissues, blood and cerebral spinal fluid as a result of anaerobic metabolism due to hypoxia. Lactate levels can therefore be used to monitor hypoxia, as increased levels are associated with a high risk of compromised vital organ function. Established cut-offs for normality and acidemia for LP used worldwide were originally proposed using a POC measurement device which is no longer available. Thus, there is an urgent need to evaluate new POCT meters and assess a safe interventional cut-off for fetal acidosis.

In this webinar we will review fetal hypoxia, the clinical value of fetal scalp blood testing and the evidence for measuring lactate over pH. We will also discuss a recent study which proposes a new cutoff for scalp lactate based on neonatal outcomes with the use of the Statstrip®/StatstripXpress® Lactate system, the only POC designed for hospital use. 

Speakers: 
Nana Wiberg, MD, Assoc Professor
Senior Consultant Obstetrics and Gynecology, American Hospital, Dubai, UAE and Lund University, Lund, Sweden 
Linda Iorizzo, MD, PhD
Department of Clinical Sciences, Lund University

Learning Objectives

  • Understand fetal hypoxia and the risks posed to newborns
  • Review the clinical value of fetal scalp blood testing of lactate
  • Learn how to interpret results
  • Evaluate new method and cut-off range

Who Should Attend

  • Obstetricians
  • Midwives
  • Neonatologists
  • Labor nurses